Organo-Metalloid Compounds
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Filtered Search Results
eMolecules 134179-38-7 | Amino-PEG3-C2-Azido | Medchem Express | MFCD00269874 | 218.257 | C8H18N4O3 | 98.000 | NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 746319562
Amino-PEG3-C2-Azido | Medchem Express | 134179-38-7 | MFCD00269874 | 218.257 | C8H18N4O3 | 98.000 | NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 746319562
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Medchemexpress LLC Azido-PEG3-SSPy | 98.6% | 344.45 g/mol | C13H20N4O3S2 | 25 MG
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Azido-PEG3-SSPy is a cleavable three-unit polyethylene glycol (PEG) linker containing an azide functional group, designed for bioconjugation and antibody-drug conjugate (ADC) synthesis. It enables click chemistry (CuAAC) and strain-promoted azide-alkyne cycloadditions (SPAAC) for attachment to alkyne- or DBCO/BCN-containing molecules.
- Cleavable disulfide-containing PEG linker suitable for ADC construction.
- Azide-functionalized for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN.
- Supplied as a colorless to light yellow liquid with high purity.
- Suitable for bioconjugation and linker development in drug conjugates.
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Medchemexpress LLC T-Boc-aminooxy-PEG5-azide | 2250216-95-4 | 95.0% | C17H34N4O8 | 50 MG
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t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an azide group for reactions
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC Bis-aminooxy-PEG3 | 98627-70-4 | 98.0% | C8H20N2O5 | 50 MG
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Bis-aminooxy-PEG3 (CAS: 98627-70-4) is a chemical compound with the molecular formula C8H20N2O5 and a molecular weight of 224.25. It is typically a colorless to light yellow liquid. This product is intended for research use only.
- Purity of 98.0% by NMR
- Store at 4°C, protected from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
- Appearance is a colorless to light yellow liquid
- Chemical structure consistent with 1H NMR and MS analysis
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Medchemexpress LLC Dbco-peg3-acid | 2754384-59-1 | 98.35% | 508.56 | 50 MG
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DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It features a DBCO group, which facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Non-cleavable 3 unit PEG ADC linker.
- Used in the synthesis of antibody-drug conjugates (ADCs).
- Contains a DBCO group.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
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Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | C28H36N8O10 | 1 MG
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Folate-PEG3-C2-acid is a specialized acid fragment derived from Folate-PEG3-NHS ester, designed as a PEG-type PROTAC linker. This compound is crucial for the synthesis of PROTAC (PROteolysis TArgeting Chimera) molecules, which are heterobifunctional molecules that induce the degradation of target proteins. Its molecular structure facilitates the creation of complex PROTACs, enabling advanced research in targeted protein degradation.
- PEG-type PROTAC linker
- Acid fragment of Folate-PEG3-NHS ester
- Essential for synthesizing PROTAC molecules
- Purity of 97.56% ensures reliable experimental results
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Medchemexpress LLC 2-(2-(2-((6-chlorohexyl)oxy)ethoxy)ethoxy)ethan-1-ol | 1355955-95-1 | MFCD32705069 | 95.0% | 268.78 g/mol | C12H25ClO4 | 250 MG
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HO-PEG3-(CH2)6-Cl is a hydroxy-terminated PEG3 linker bearing a six-carbon chlorinated alkyl chain, used as a building block in PROTAC and bioconjugation chemistry. It serves as a flexible, hydrophilic spacer for attaching ligands, tags, or warheads during linker assembly and small-scale synthesis.
- Polyethylene glycol (PEG3) spacer with terminal hydroxy and six-carbon chloride.
- Designed for PROTAC linker assembly and bioconjugation.
- Flexible and hydrophilic to improve solubility and spacing between functional groups.
- Supplied in research-scale packs suitable for method development and small-scale synthesis.
- Molecular formula C12H25ClO4; molecular weight 268.78 g/mol.
- CAS number 1355955-95-1; supplier-reported purity typically 95%.
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Medchemexpress LLC PEG3-C4-OBn | 2381196-79-6 | 99.3% | 100 MG
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It can be used in the synthesis of the PROTAC SGK3 degrader-1, which is a potent SKG3 degrader.
- Polyethylene glycol (PEG)-based PROTAC linker
- Used in the synthesis of PROTAC SGK3 degrader-1
- High solubility in DMSO (≥ 100 mg/mL)
- Long-term stability in pure form at -20°C (3 years) and 4°C (2 years)
- Extended stability in solvent at -80°C (6 months) and -20°C (1 month)
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Medchemexpress LLC I-PEG5-OH 100mg
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC Tos-PEG5-Boc | 581065-94-3 | ≥97.0% | 250 MG
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Tos-PEG5-Boc is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase and a ligand for the target protein. It has a molecular weight of 476.58 and a chemical formula of C22H36O9S. Its appearance is a viscous liquid, colorless to light yellow.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- Viscous liquid, colorless to light yellow appearance
- For research use only
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 hydrochloride | 2446474-09-3 | 96.6% | 250 MG
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Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a 3-unit PEG linker used in PROTAC technology.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a Pomalidomide-based cereblon ligand
- Includes a 3-unit PEG linker
- Used in PROTAC technology
- Appears as a light yellow to yellow solid
- Structure consistent by 1H NMR spectrum
- Structure consistent by LCMS
- Purity of 96.6% by LCMS
- For research use only
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Ambeed AMBEED
5000891646 TETRAETHYL BUTANE-14-DIY 100MG
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Medchemexpress LLC 14-azido-3,6,9,12-tetraoxatetradecan-1-ol | 86770-68-5 | 97.0% | 263.29 g/mol | C10H21N3O5 | 1 G
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Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker with a terminal azide and a terminal alcohol, used for bioconjugation and linker installation. The azide group enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions, while the PEG5 spacer improves solubility and flexibility for conjugation workflows.
- Terminal azide enables CuAAC and SPAAC click reactions.
- PEG5 spacer increases solubility and reduces steric hindrance.
- Suitable for use as a non-cleavable linker in conjugation chemistry.
- Colorless to light yellow liquid with high purity.
- Stable under recommended storage conditions for long-term use.
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eMolecules METHYLDIETHOXYSILANE 5G
5000188369 METHYLDIETHOXYSILANE 5G
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eMolecules TOS-PEG5 T-BUTYL ESTER 25G
5000193072 TOS-PEG5 T-BUTYL ESTER 25G
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